Yayıncı "Springer" TF, Temel Tıp Bilimleri Bölümü Koleksiyonu için listeleme
Toplam kayıt 32, listelenen: 1-20
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Agomelatine on cisplatin-induced nephrotoxicity via oxidative stress and apoptosis
(Springer, 2023)Drug-induced nephrotoxicity is the greatest deterrent to the use of cisplatin, which is a frequently used chemotherapeutic with proven efectiveness in cancer therapy. Agomelatine, which is used in the treatment of sleep ... -
Assessment of peripapillary retinal nerve fiber layer thickness in children with vitamin B-12 deficiency
(Springer, 2013)Vitamin B-12 deficiency is a worldwide problem. It affects all ages, including children. It is one of the most common nutritional disorders and can cause harmful effects on the nervous system. in this study, we compared ... -
Can dexmedetomidine be effective in the protection of radiotherapy-induced brain damage in the rat?
(Springer, 2021)Approximately 7 million people are reported to be undergoing radiotherapy (RT) at any one time in the world. However, it is still not possible to prevent damage to secondary organs that are off-target. This study, therefore, ... -
Characterization of tetracycline resistance genes in tetracycline-resistant Enterobacteriaceae obtained from a coliform collection
(Springer, 2010)Tetracycline resistance has been used as the key determinant to monitor resistance genes in natural environments such as rivers, lakes or seawater. The aim of this study was evaluate the frequency of tetA, tetB, tetC, tetD ... -
Cholesterol forms and traditional lipid profile for projection of atherogenic dyslipidemia: lipoprotein subfractions and erythrocyte membrane cholesterol
(Springer, 2014)Atherogenic dyslipidemia characterized by abnormal changes in plasma lipid profile such as low high-density lipoprotein (HDL) and increased triglyceride (TG) levels is strongly associated with atherosclerotic diseases. We ... -
Comparative analysis of epigallocatechin-3-gallate and TNF-alpha inhibitors in mitigating cisplatin-induced pancreatic damage through oxidative stress and apoptosis pathways
(Springer, 2024)Oxidative stress and inflammation caused by cisplatin, which is frequently used in the treatment of many cancers, damage healthy tissues as well as cancer cells. In this study, we aimed to investigate the effect of ... -
Comparison of a novel antigen detection test with reverse transcription polymerase chain reaction assay for laboratory diagnosis of SARS-CoV-2 infection
(Springer, 2022)Molecular diagnosis of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) by real-time reverse transcription polymerase chain reaction (RT-PCR) in respiratory specimens is considered the gold standard method. ... -
Comparison of effects of dexmedetomidine and amifostine against X-ray radiation-induced parotid damage
(Springer, 2022)Radiotherapy can be employed as a therapeutic modality alone in the early stages of cancer and is used together with other treatments such as surgery and chemotherapy in more advanced stages. However, exposure to ionizing ... -
Determination of the cytotoxicity and antibiofilm potential effect of equisetum arvense silver nanoparticles
(Springer, 2023)This study aimed to synthesize and characterize silver nanoparticles (AgNPs) by green synthesis from Equisetum arvense (Ea) extracts and to investigate their cytotoxicity, antibiofilm activity, and alpha-glucosidase enzyme ... -
The effects of Atorvastatin Therapy on rheological characteristics of erythrocyte Membrane, serum lipid profile and oxidative status in patients with dyslipidemia
(Springer, 2012)The statins, most commonly used in the treatment of hyperlipidemia, have certain beneficial effects including improved endothelial function, plaque stability and decreased oxidative stress and inflammation, beyond their ... -
The effects of carvacrol on transient receptor potential (TRP) channels in an animal model of parkinson's disease
(Springer, 2023)In this study, we aimed to investigate the effects of carvacrol (CA), a widely used phytochemical having anti-oxidant and neuroprotective effects, on transient receptor potential (TRP) channels in an animal model of ... -
Effects of copaene, a tricyclic sesquiterpene, on human lymphocytes cells in vitro
(Springer, 2014)In this study, the cytotoxic, genotoxic/antigenotoxic and antioxidant/oxidant activity of copaene (COP), a plant-derived tricyclic sesquiterpene, on human lymphocyte cultures (n = 5) was investigated. COP was added into ... -
Effects of gadolinium-based contrast agents on submandibular gland tissue in rats
(Springer, 2018)The aim of this prospective animal study is to investigate the influence of multiple administrations of macrocyclic ionic (gadoteric acid) and linear nonionic (gadodiamide) gadolinium-based contrast agents (GBCA) on ... -
Effects of sugammadex on immunoreactivity of calcineurin in rat testes cells after neuromuscular block: A pilot study
(Springer, 2012)Reversal of neuromuscular blockage induced by steroidal neuromuscular blocking agents such as rocuronium can be achieved using normal dose of sugammadex, which has been shown to be very effective for such reversal. In this ... -
An electrochemical immuno-cytosensor modified with nanofibers for the determination of a carcinoembryonic antigen
(Springer, 2024)In this study, La0.25Fe0.75FeO3 (PNp)perovskite nanoparticle was synthesized using the sol–gel method. PNp-coated polyacrylonitrile (PAN) nanofibers were prepared by electrospinning on the pencil graphite electrode (PGE) ... -
Evaluation of periostin, fibronectin and tenascin-C in patients chronic otitis media with cholesteatoma
(Springer, 2022)Background: Although many studies have investigated the mechanisms of cholesteatoma formation, its pathogenesis remains unclear. The aim of this study was to evaluate the levels of periostin, fibronectin and tenascin-C, ... -
Evaluation of serum semaphorin 3A and interleukin 6 levels in patients with pseudoexfoliation syndrome
(Springer, 2023)Purpose: To evaluate serum semaphorin 3A (Sema3A) and interleukin 6 (IL-6) levels in pseudoexfoliation syndrome (PXS) patients to determine whether these mediators play a role in the systemic manifestations of PXS. Methods: ... -
The histomorphological and stereological assessment of rat dorsal root ganglion tissues after various types of sciatic nerve injury
(Springer, 2023)Peripheral nerve injuries lead to signifcant changes in the dorsal root ganglia, where the cell bodies of the damaged axons are located. The sensory neurons and the surrounding satellite cells rearrange the composition ... -
The impact of apelin-13 on cisplatin-induced endocrine pancreas damage in rats: an in vivo study
(Springer, 2024)Apelin-13 is a peptide hormone that regulates pancreatic endocrine functions, and its benefits on the endocrine pancreas are of interest. This study aims to investigate the potential protective effects of apelin-13 in ...