Ara
Toplam kayıt 246, listelenen: 91-100
Repurposing ibudilast in combination with temozolomide for glıoblastoma
(Oxford Univ Press Inc, 2016)
Aims: Recurrence in patients with Glioblastoma (GBM) is
inevitable, even in patients with O-6-Methylguanine-DNA
Methyl Transferase (MGMT) methylation.
Gene expression and histopathological evaluation of thiamine pyrophosphate on optic neuropathy induced with ethambutol in rats
(Ijo Press, 2016)
AIM: To compare the effects of thiamine pyrophosphate (TPP) and thiamine (TM) in oxidative optic neuropathy in rats induced by ethambutol. METHODS: the animals were divided into four groups: a control group (CG), an ...
The effects of monosodium glutamate and tannic acid on adult rats
(Kowsar Publ, 2016)
Background: Monosodium glutamate (MSG) is a widely-used flavor enhancer and stabilizer in ready-made or packaged foods. the excessive use of MSG has been shown to increase oxidative stress in different organ systems and ...
Effects of nimesulide on the small intestine mucositis induced by methotrexate in rats
(Int Press Editing Centre Inc, 2016)
Intestinal mucositis is one of the major problems in the patients receiving cancer treatment. Nimesulide is a drug with antioxidant, antiinflammatory and antiulcer features. We aimed to investigate the effect of nimesulide ...
Histopathological effects of intramuscular metamizole sodium on rat sciatic nerve
(Mashhad Univ Med Sciences, 2016)
Objective(s): We investigated the histopathological effects of metamizole sodium (MS) on the sciatic nerve. Materials and Methods: This study was performed using 48 adult male Wistar albino rats. Ten groups were constituted ...
The protective effect of adalimumab on renal injury in a model of abdominal aorta cross-clamping
(Wroclaw Medical Univ, 2016)
Background. Adalimumab (ADA) is a potent inhibitor of tumor necrosis factor (TNF-alpha). ADA treatment suppresses proinflammatory cytokines, leading to a decrease or inhibition of the inflammatory process. Objectives. the ...
Protective effects of thymoquinone and alpha-tocopherol on the sciatic nerve and femoral muscle due to lower limb ischemia-reperfusion injury
(Verduci Publisher, 2016)
OBJECTIVE: Thymoquinone (TQ) is an antioxidant and anti-apoptotic substance found in the Nigella sativa plant. Alpha-tocopherol (alpha-TP) is a potent antioxidant. We aimed to determine whether or not TQ and TP have a ...
Contribution of myeloperoxidase and inducible nitric oxide synthase to pathogenesis of psoriasis
(Termedia Publishing House Ltd, 2016)
Introduction: Histological changes of psoriasis include invasion of neutrophils into the epidermis and formation of Munro abscesses in the epidermis. Neutrophils are the predominant white blood cells in circulation when ...
Alteration of maternal serum irisin levels in gestational diabetes mellitus
(Via Medica, 2016)
Objectives: the aim of our study was to compare serum irisin concentrations in pregnant women with and without gestational diabetes mellitus (GDM). Material and methods: This study was performed at the Tertiary Care Center, ...
Comparison of verona integron-borne metallo-beta-lactamase (VIM) variants reveals differences in stability and inhibition profiles
(Amer Soc Microbiology, 2016)
Metallo-beta-lactamases (MBLs) are of increasing clinical significance; the development of clinically useful MBL inhibitors is challenged by the rapid evolution of variant MBLs. the Verona integron-borne metallo-beta-lactamase ...