Browsing by Author "Sandallı, Cemal"
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Anthocyanins profiling of Thymus praecox opiz subsp caucasicus var. caucasicus
Turumtay, Emine Akyüz; Turumtay, Halbay; Demir, Adem; Selvi, Emine Kılıçkaya; Yazıcı, Emre; Sandallı, Cemal; Yazıcı, Zihni Açar (Elsevier Science Bv, 2015)Thymus praecox Opiz subsp. caucasicus var. caucasicus (Anzer tea) was studied to determine its anthocyanin content; anthocyanin stability in response to acidic hydrolysis and temperature changes. in this study, anthocyanin ... -
Antibiotic resistance profiles of enteric bacteria Isolated from Kucukcekmece Lagoon (Istanbul – Turkey)
Bu çalışmanın amacı, Küçükçekmece Lagünü’ndeki (İstanbul) fekal bakteri yoğunluğunu bulmak ve izole edilen Gram negatif basillerin antibiyotiklere direncini analiz etmektir. Örnekler, Haziran 2006'dan Haziran 2008 tarihleri ... -
Antibiotic resistance profiles of enteric cacteria isolated from Kucukcekmece Lagoon (Istanbul-Turkey)
Sivri, Nuket; Sandallı, Cemal; Özgümüş, Osman Birol; Çolakoğlu, Feyza; Doğan, Dilek (Central Fisheries Research Inst, 2012)The aim of this study is to find out the density of the fecal bacteria and to analyze resistance to antimicrobials of Gram negative bacilli isolated from the Kucukcekmece Lagoon, Istanbul. Samples were taken monthly from ... -
Antimicrobial resistance patterns and integron carriage of escherichia coli isolates causing community-acquired infections in Turkey
Çiçek, Ayşegül Çopur; Özgümüş, Osman Birol; Saral, Ayşegül; Sandallı, Cemal (Korean Soc Laboratory Medicine, 2014)We aimed to observe antimiCrobial resistance patterns and integron carriage of Escherichia coli isolates causing community-acquired infections. Two hundred sixty-eight E. coli strains were obtained from outpatients with ... -
Carriage of class 1 and 2 integrons in acinetobacter baumannii and pseudomonas aeruginosa isolated from clinical specimens and a novel gene cassette array: bla(OXA-11)-cmlA7
Mengeloğlu, Fırat Zafer; Çiçek, Ayşegül Çopur; Koçoğlu, Esra; Sandallı, Cemal; Budak, Emine Esra; Özgümüş, Osman Birol (Ankara Microbiology Soc, 2014)The dissemination of antibiotic resistance genes between bacteria leads to serious problems in the treatment of infectious diseases. It has been shown that resistance genes can also be carried by the integrons. There are ... -
Characterızatıon of catalytıc carboxylate trıad ın non-replıcatıve dna polymerase III (pol E) of Geobacillus kaustophilus HTA
Sandallı, Cemal; Singh, Kamalendra; Modak, Mukund J. (C M B Assoc, 2012)Three aspartic acid residues D378, D380 and D531 form the catalytic carboxylate triad in Geobacillus kaustophilus (Gka) DNA polymerase III alpha-subunit homolog, pol E. We cloned, expressed and purified wild type (WT), ... -
Cloning, expression, and characterization of a novel CTP synthase gene from Anoxybacillus gonensis G2
Sandallı, Cemal; Saral, Ayşegül; Ülker, Serdar; Karaoğlu, Hakan; Beldüz, Ali Osman; Çiçek, Ayşegül Çopur (2014)The cytidine-5'-triphosphate (CTP) synthase (EC 6.4.3.2) gene (pyrG) was cloned and sequenced from the thermophilic bacterium Anoxybacillus gonensis G2 (Ago). The gene is 1590 bp in length and encodes a protein of 530 amino ... -
Cloning, purification and characterization of acetyl Xylane esterase from anoxybacillus flavithermus DSM 2641(T) with activity on low molecular-weight acetates
Eminoğlu, Ayşenur; Ülker, Serdar; Sandallı, Cemal (Springer, 2015)Family 4 carbohydrate esterases (CE-4) have deacetylate different forms of acetylated poly/oligosaccharides in nature. This family is recognized with a specific polysaccharide deacetylase domain assigned as NodB homology ... -
Determination of a novel integron-located variant (bla(OXA-320)) of class D beta-lactamase in Proteus mirabilis
Çiçek, Ayşegül Çopur; Düzgün, Azer Özad; Saral, Ayşegül; Sandallı, Cemal (Wiley, 2014)Proteus mirabilis (P. mirabilis) is one of Gram-negative pathogens encountered in clinical specimens. A clinical isolate (TRP41) of P. mirabilis was isolated from a Turkish patient in Turkey. the isolate was identified ... -
Distribution of beta-lactamase genes among carbapenem-resistant klebsiella pneumoniae strains isolated from patients in Turkey
Iraz, Meryem; Düzgün, Azer Özad; Sandallı, Cemal; Doymaz, Mehmet Ziya; Akkoyunlu, Yasemin; Saral, Ayşegül; Peleg, Anton Y.; Özgümüş, Osman Birol; Beriş, Fatih Şaban; Karaoğlu, Hakan; Çiçek, Ayşegül Çopur (Korean Soc Laboratory Medicine, 2015)Background: the emergence of carbapenem-resistant Klebsiella pneumoniae poses a serious problem to antibiotic management. We investigated the beta-lactamases in a group of carbapenem-resistant K. pneumoniae clinical isolates ... -
İdrar Kültürlerinden İzole Edilen EscherichiacoliSuşlarında Sınıf 1 ve Sınıf 2 İntegron Gen Kasetlerinin Karakterizasyonu: Çok Merkezli Bir Çalışma
Çopur, Ayşegül Çiçek; Sandallı, Cemal; Budak, Emine Esra; Yağmur, Gülhan; Çizmeci, Zeynep; Ak, Sibel; Özgümüş, Osman Birol (2016)Escherichia coli hem hastane hem de toplum kaynaklı üriner sistem enfeksiyonlarında en sık izole edilen etkendir. Ülkemizde E.coli suşlarının antibiyotik duyarlılıkları ile ilgili farklı merkezlerde yapılmış çok sayıda ... -
Klinik örneklerden izole edilen trimetoprim-sülfametoksazole dirençli stenotrophomonas maltophilia suşlarında integron, sul1-2 ve dfr genlerinin araştırılması
Özkaya, Esra; Aydın, Faruk; Bayramoğlu, Gülçin; Buruk, Celal Kurtuluş; Sandallı, Cemal (Ankara Microbiology Soc, 2014)Stenotrophomonas maltophilia, which is a non-fermentative gram-negative bacillus, has an increasing importance in nosocomial and opportunistic infections. Since it exhibits resistance to numerous broad-spectrum antibiotics ... -
Klinik örneklerden izole edilen acinetobacter baumannii ve pseudomonas aeruginosa suşlarının sınıf 1 ve 2 integron taşıyıcılığı ve yeni bir gen kaseti birlikteliği: blaOXA-11-cmlA7
Mengeloğlu, Fırat Zafer; Çiçek, Ayşegül Çopur; Koçoğlu, Mücahide Esra; Sandallı, Cemal; Budak, Emine Esra; Özgümüş, Osman Birol (2014)Antibiyotik direnç genlerinin bakteriler arasındaki yayılımı, enfeksiyon hastalıklarının tedavisinde ciddi sorunlar oluşturmaktadır. Son zamanlarda bu genlerin integronlarda da taşındığı gösterilmiştir. Ülkemizde, Acinetobacter ... -
Klinik örneklerden izole edilen Trimetoprim-sülfametoksazole dirençli Stenotrophomonas maltophilia suşlarında integron, sul1-2 ve dfr genlerinin araştırılması
Nonfermentatif gram-negatif basil olan Stenotrophomonas maltophilia, hastane enfeksiyonları ve fırsatçı enfeksiyonlar açısından giderek artan bir öneme sahiptir. Çeşitli mekanizmaları kullanarak aminoglikozidler, beta-laktamlar, ... -
Molecular characterisation and control of Acinetobacter baumannii isolates resistant to multi-drugs emerging in inter-intensive care units
Ertürk, Ayşe; Çiçek, Ayşegül Çopur; Gümüş, Aziz; Cüre, Erkan; Şen, Ahmet; Kurt, Aysel; Karagöz, Alper; Aydoğan, Nebahat; Sandallı, Cemal; Durmaz, Rıza (BmcBMC, 2014)Background: A nosocomial outbreak of Acinetobacter baumannii (AB) infections occurred among intensive care units (ICU) (surgery, medical, cardiovascular surgery, coronary unit) of Recep Tayyip Erdogan University Medical ... -
Nationwide study of Escherichia coli producing extended-spectrum beta-lactamases TEM, SHV and CTX-M in Turkey
Çiçek, Ayşegül Çopur; Saral, Ayşegül; Düzgün, Azer Özad; Yaşar, Ekrem; Çizmeci, Zeynep; Balcı, Pervin Özlem; Sarı, Fatma; Fırat, Mehmet; Altıntop, Yasemin Ay; Ak, Sibel; Çalışkan, Ahmet; Yıldız, Nazan; Sancaktar, Metin; Budak, Emine Esra; Ertürk, Ayşe; Özgüm, Osman Birol; Sandallı, Cemal (Nature Publishing Group, 2013)Four hundred and forty extended-spectrum beta-lactamase (ESBL)-producing Escherichia coli isolates were collected from 10 different hospitals in Turkey between 2011 and 2012. Clinical specimens consisted of urine (80.45%), ... -
OXA- and GES-type beta-lactamases predominate in extensively drug-resistant Acinetobacter baumannii isolates from a Turkish University Hospital
Çiçek, Ayşegül Çopur; Saral, Ayşegül; Iraz, Meryem; Ceylan, Ayşenur; Düzgün, Azer Özad; Peleg, Anton Y.; Sandallı, Cemal (Elsevier Sci Ltd, 2014)We determined the antibiotic susceptibility and genetic mechanisms of resistance in clinical strains of Acinetobacter baumannii from Istanbul, Turkey. A total of 101 clinical strains were collected between November 2011 ... -
PaCaHa inhibits proliferation of human cancer cells in vitro
Background/aim: The aim of this study was to investigate the antiproliferative and cytotoxic effects of a newly synthesized molecule named paracetamol acetohydroxamic acid (PaCaHa) on human neoplastic cell lines. Materials ... -
Studies on synthesis, structure, and DNA cleaving of homo-dinuclear Mn(II), Cu(II), Ni(II), and Zn(II) complexes with a heterocycle-based macroacyclic Schiff base
Baran, Talat; Karaoğlu, Kaan; Serbest, Kerim; Ağır, Hülya; Sandallı, Cemal; Değirmencioğlu, İsmail (Springer Wien, 2013)(E,E',E'',E''')-N,N',N'',N'''-[(1,2-ethenyliden)tetrakis[methylenoxy(2,1-naphthalinediyl)methylidyne]tetrakis[1,2,4-triazol-4-amine] and its novel homo-dinuclear Mn(II), Ni(II), Cu(II), and Zn(II) complexes have been ...
